Visceral and ectopic fat, atherosclerosis, and cardiometabolic disease: a position statement

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Citações na Scopus
650
Tipo de produção
article
Data de publicação
2019
DOI
Scopus
Web of Science
PubMed
Título da Revista
ISSN da Revista
Título do Volume
Editora
ELSEVIER SCIENCE INC
Autores
NEELAND, Ian J.
ROSS, Robert
DESPRES, Jean-Pierre
MATSUZAWA, Yuji
YAMASHITA, Shizuya
SHAI, Iris
SEIDELL, Jaap
MAGNI, Paolo
ARSENAULT, Benoit
Citação
LANCET DIABETES & ENDOCRINOLOGY, v.7, n.9, p.715-725, 2019
Projetos de Pesquisa
Unidades Organizacionais
Fascículo
Resumo
Findings from epidemiological studies over the past 30 years have shown that visceral adipose tissue, accurately measured by CT or MRI, is an independent risk marker of cardiovascular and metabolic morbidity and mortality. Emerging evidence also suggests that ectopic fat deposition, including hepatic and epicardial fat, might contribute to increased atherosclerosis and cardiometabolic risk. This joint position statement from the International Atherosclerosis Society and the International Chair on Cardiometabolic Risk Working Group on Visceral Obesity summarises the evidence for visceral adiposity and ectopic fat as emerging risk factors for type 2 diabetes, atherosclerosis, and cardiovascular disease, with a focus on practical recommendations for health professionals and future directions for research and clinical practice. We discuss the measurement of visceral and ectopic fat, pathophysiology and contribution to adverse health outcomes, response to treatment, and lessons from a public health programme targeting visceral and ectopic fat. We identify knowledge gaps and note the need to develop simple, clinically applicable tools to be able to monitor changes in visceral and ectopic fat over time. Finally, we recognise the need for public health messaging to focus on visceral and ectopic fat in addition to excess bodyweight to better combat the growing epidemic of obesity worldwide.
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URI
https://observatorio.fm.usp.br/handle/OPI/33434
Referências
  1. ABATE N, 1995, J CLIN INVEST, V96, P88, DOI 10.1172/JCI118083
  2. Adiels M, 2008, ARTERIOSCL THROM VAS, V28, P1225, DOI 10.1161/ATVBAHA.107.160192
  3. Alberti KGMM, 2005, LANCET, V366, P1059, DOI 10.1016/S0140-6736(05)67402-8
  4. Arita Y, 1999, BIOCHEM BIOPH RES CO, V257, P79, DOI 10.1006/bbrc.1999.0255
  5. Arsenault BJ, 2012, ANN MED, V44, P758, DOI 10.3109/07853890.2011.605387
  6. ASHWELL M, 1985, BRIT MED J, V290, P1692, DOI 10.1136/bmj.290.6483.1692
  7. Batetta B, 2009, J NUTR, V139, P1495, DOI 10.3945/jn.109.104844
  8. Bays HE, 2011, J AM COLL CARDIOL, V57, P2461, DOI 10.1016/j.jacc.2011.02.038
  9. Bays HE, 2019, OBESITY ALGORITHM SL
  10. Benjamin EJ, 2018, CIRCULATION, V137, pE67, DOI 10.1161/CIR.0000000000000558
  11. BORKAN GA, 1982, AM J CLIN NUTR, V36, P172
  12. Brauer P, 2015, CAN MED ASSOC J, V187, P184, DOI 10.1503/cmaj.140887
  13. Britton KA, 2011, CIRCULATION, V124, pE837, DOI 10.1161/CIRCULATIONAHA.111.077602
  14. Brochu M, 2009, J CLIN ENDOCR METAB, V94, P3226, DOI 10.1210/jc.2008-2706
  15. Chaston TB, 2008, INT J OBESITY, V32, P619, DOI 10.1038/sj.ijo.0803761
  16. Cowan TE, 2018, OBESITY, V26, P1696, DOI 10.1002/oby.22304
  17. Cuthbertson DJ, 2017, INT J OBESITY, V41, P853, DOI 10.1038/ijo.2017.4
  18. Despres JP, 2008, ARTERIOSCL THROM VAS, V28, P1039, DOI 10.1161/ATVBAHA.107.159228
  19. Despres JP, 2006, NATURE, V444, P881, DOI 10.1038/nature05488
  20. Despres JP, 2012, CIRCULATION, V126, P1301, DOI 10.1161/CIRCULATIONAHA.111.067264
  21. Despres JP, 2012, J CLIN ENDOCR METAB, V97, P2283, DOI 10.1210/jc.2012-2081
  22. DESPRES JP, 1989, DIABETES, V38, P304, DOI 10.2337/diabetes.38.3.304
  23. DESPRES JP, 1990, ARTERIOSCLEROSIS, V10, P497, DOI 10.1161/01.ATV.10.4.497
  24. Dongiovanni P, 2015, HEPATOLOGY, V61, P506, DOI 10.1002/hep.27490
  25. Eslam M, 2018, J HEPATOL, V68, P268, DOI 10.1016/j.jhep.2017.09.003
  26. Fabbrini E, 2009, P NATL ACAD SCI USA, V106, P15430, DOI 10.1073/pnas.0904944106
  27. Fox CS, 2007, CIRCULATION, V116, P39, DOI 10.1161/CIRCULATIONAHA.106.675355
  28. FUJIOKA S, 1987, METABOLISM, V36, P54, DOI 10.1016/0026-0495(87)90063-1
  29. Garvey WT, 2016, ENDOCR PRACT, V22, P1, DOI 10.4158/EP161365.GL
  30. Gasteyger C, 2009, DIABETES OBES METAB, V11, P596, DOI 10.1111/j.1463-1326.2008.01025.x
  31. GBD, 2015, NEW ENGL J MED, V377, P13, DOI [10.1056/NEJMoa1614362, DOI 10.1056/NEJMOA1614362]
  32. Gepner Y, 2018, CIRCULATION, V137, P1143, DOI 10.1161/CIRCULATIONAHA.117.030501
  33. Gonzalez-Muniesa P, 2017, NAT REV DIS PRIMERS, V3, DOI 10.1038/nrdp.2017.34
  34. Gradmark AMI, 2010, BRIT J NUTR, V104, P582, DOI 10.1017/S0007114510000796
  35. Grundy SM, 2005, CIRCULATION, V112, P2735, DOI 10.1161/CIRCULATIONAHA.105.169404
  36. Hammond BP, 2017, BODY COMPOSITION: HEALTH AND PERFORMANCE IN EXERCISE AND SPORT, P109
  37. Heymsfield SB, 2015, P NUTR SOC, V74, P355, DOI 10.1017/S0029665115000129
  38. Hiuge-Shimizu A, 2012, ANN MED, V44, P82, DOI 10.3109/07853890.2010.526138
  39. Iacobellis G, 2011, TRENDS ENDOCRIN MET, V22, P450, DOI 10.1016/j.tem.2011.07.003
  40. Irving BA, 2008, MED SCI SPORT EXER, V40, P1863, DOI 10.1249/MSS.0b013e3181801d40
  41. Janiszewski PM, 2007, APPL PHYSIOL NUTR ME, V32, P512, DOI 10.1139/H07-018
  42. Janssen I, 2002, CAN J APPL PHYSIOL, V27, P396, DOI 10.1139/h02-021
  43. Janssen I, 2001, MED SCI SPORT EXER, V33, pS5, DOI 10.1097/00005768-200105001-00027
  44. Jensen MK, 2013, CIRCULATION, V127, DOI 10.1161/01.cir.0000437739.71477.ee
  45. Kaul S, 2012, OBESITY, V20, P1313, DOI 10.1038/oby.2011.393
  46. Kay SJ, 2006, OBES REV, V7, P183, DOI 10.1111/j.1467-789X.2006.00250.x
  47. Keating SE, 2015, J HEPATOL, V63, P174, DOI [10.1016/j.jhep.2015.03.009, 10.1016/j.jhep.2015.02.022]
  48. Kishida K, 2000, J BIOL CHEM, V275, P20896, DOI 10.1074/jbc.M001119200
  49. Klein S, 2010, DIABETES CARE, V33, P1693, DOI 10.2337/dc10-0744
  50. Kotronen A, 2008, ARTERIOSCL THROM VAS, V28, P27, DOI 10.1161/ATVBAHA.107.147538
  51. Kozlitina J, 2014, NAT GENET, V46, P352, DOI 10.1038/ng.2901
  52. Kuda O, 2018, MOL ASPECTS MED, V64, P147, DOI 10.1016/j.mam.2018.01.004
  53. Kuriyama H, 1998, HEPATOLOGY, V27, P557, DOI 10.1002/hep.510270233
  54. Lauridsen BK, 2018, EUR HEART J, V39, P385, DOI 10.1093/eurheartj/ehx662
  55. Lee JJ, 2016, J AM COLL CARDIOL, V68, P1509, DOI 10.1016/j.jacc.2016.06.067
  56. Lemieux I, 2000, CIRCULATION, V102, P179, DOI 10.1161/01.CIR.102.2.179
  57. Lemieux I, 2007, CAN J CARDIOL, V23, p23B, DOI 10.1016/S0828-282X(07)71007-3
  58. Linge J, 2018, OBESITY, V26, P1785, DOI 10.1002/oby.22210
  59. Mahabadi AA, 2013, J AM COLL CARDIOL, V61, P1388, DOI 10.1016/j.jacc.2012.11.062
  60. Mathieu P, 2014, REV ENDOCR METAB DIS, V15, P289, DOI 10.1007/s11154-014-9299-3
  61. Matsuzawa Y, 1997, DIABETES METAB REV, V13, P3, DOI 10.1002/(SICI)1099-0895(199703)13:1<3::AID-DMR178>3.0.CO;2-N
  62. Matsuzawa Y, 2011, J ATHEROSCLER THROMB, V18, P629, DOI 10.5551/jat.7922
  63. Merlotti C, 2017, INT J OBESITY, V41, P672, DOI 10.1038/ijo.2017.31
  64. Mongraw-Chaffin M, 2018, J AM COLL CARDIOL, V71, P1857, DOI 10.1016/j.jacc.2018.02.055
  65. Nazare JA, 2015, AM J CARDIOL, V115, P307, DOI 10.1016/j.amjcard.2014.10.039
  66. Ndumele CE, 2011, ARTERIOSCL THROM VAS, V31, P1927, DOI 10.1161/ATVBAHA.111.228262
  67. Neeland IJ, 2016, NUTR DIABETES, V6, DOI 10.1038/nutd.2016.28
  68. Neeland IJ, 2018, CIRCULATION, V137, P1391, DOI 10.1161/CIRCULATIONAHA.117.029617
  69. Neeland IJ, 2017, METABOLISM, V67, P80, DOI 10.1016/j.metabol.2016.11.008
  70. Neeland IJ, 2015, DIABETES THER, V6, P635, DOI 10.1007/s13300-015-0146-7
  71. Neeland IJ, 2013, OBESITY, V21, pE439, DOI [10.1038/oby.20135, 10.1002/oby.20135]
  72. O'Neill T, 2013, EXERCISE THERAPY ADU, P43
  73. Ohkawara K, 2007, INT J OBESITY, V31, P1786, DOI 10.1038/sj.ijo.0803683
  74. Okauchi Y, 2013, J DIABETES INVEST, V4, P454, DOI 10.1111/jdi.12084
  75. Okauchi Y, 2010, ATHEROSCLEROSIS, V212, P698, DOI 10.1016/j.atherosclerosis.2010.06.011
  76. Ouchi N, 2011, NAT REV IMMUNOL, V11, P85, DOI 10.1038/nri2921
  77. Posadas-Sanchez R., 2016, GEA STUDY IMMUNOBIOL, V222, P960
  78. POULIOT MC, 1994, AM J CARDIOL, V73, P460, DOI 10.1016/0002-9149(94)90676-9
  79. Preis SR, 2010, J CLIN ENDOCR METAB, V95, P3701, DOI 10.1210/jc.2009-1779
  80. Ross R, 2004, OBES RES, V12, P789, DOI 10.1038/oby.2004.95
  81. Ross R, 2008, OBES REV, V9, P312, DOI 10.1111/j.1467-789X.2007.00411.x
  82. ROSS R, 1994, AM J CLIN NUTR, V59, P1277
  83. Ross R, 2002, J CLIN ENDOCR METAB, V87, P5044, DOI 10.1210/jc.2002-020570
  84. Ross R, 2000, ANN INTERN MED, V133, P92, DOI 10.7326/0003-4819-133-2-200007180-00008
  85. ROSS R, 2002, AM J PHYSIOL-ENDOC M, V282, pE65
  86. Ross R, 2015, ANN INTERN MED, V162, P325, DOI 10.7326/M14-1189
  87. Ryo M, 2011, INTERNAL MED, V50, P1643, DOI 10.2169/internalmedicine.50.5039
  88. Sabag A, 2017, DIABETES METAB, V43, P195, DOI 10.1016/j.diabet.2016.12.006
  89. Schauer PR, 2017, NEW ENGL J MED, V376, P641, DOI 10.1056/NEJMoa1600869
  90. SJOSTROM L, 1986, AM J PHYSIOL, V250, pE736
  91. Slentz CA, 2005, J APPL PHYSIOL, V99, P1613, DOI 10.1152/japplphysiol.00124.2005
  92. Smith U, 2016, J INTERN MED, V280, P465, DOI 10.1111/joim.12540
  93. Snijder MB, 2006, INT J EPIDEMIOL, V35, P83, DOI 10.1093/ije/dyi253
  94. Targher G, 2017, NAT REV NEPHROL, V13, P297, DOI 10.1038/nrneph.2017.16
  95. Taylor R, 2016, EXPERT REV ENDOCRINO, V11, P521, DOI 10.1080/17446651.2016.1239525
  96. Taylor R, 2015, CLIN SCI, V128, P405, DOI 10.1042/CS20140553
  97. Tchernof A, 2013, PHYSIOL REV, V93, P359, DOI 10.1152/physrev.00033.2011
  98. Thompson D, 2012, PHYSIOL REV, V92, P157, DOI 10.1152/physrev.00012.2011
  99. Tilg H, 2017, NAT REV GASTRO HEPAT, V14, P32, DOI 10.1038/nrgastro.2016.147
  100. TOKUNAGA K, 1983, INT J OBESITY, V7, P437
  101. Tsigos C, 2008, OBESITY FACTS, V1, P106, DOI 10.1159/000126822
  102. Umpleby AM, 2017, CLIN SCI, V131, P2561, DOI 10.1042/CS20171208
  103. Valenti L, 2016, LIVER INT, V36, P1563, DOI 10.1111/liv.13185
  104. Vasan SK, 2016, NAT REV ENDOCRINOL, V12, P375, DOI 10.1038/nrendo.2016.77
  105. Verheggen RJHM, 2016, OBES REV, V17, P664, DOI 10.1111/obr.12406
  106. Villeneuve N, 2014, APPL PHYSIOL NUTR ME, V39, P503, DOI 10.1139/apnm-2013-0270
  107. Vissers D, 2013, PLOS ONE, V8, DOI 10.1371/journal.pone.0056415
  108. Wildman RP, 2008, ARCH INTERN MED, V168, P1617, DOI 10.1001/archinte.168.15.1617
  109. Wong CX, 2016, CIRC-ARRHYTHMIA ELEC, V9, DOI 10.1161/CIRCEP.116.004378
  110. Yang L, 2010, CLIN ENDOCRINOL, V73, P197, DOI 10.1111/j.1365-2265.2009.03772.x

Coleções
Artigos e Materiais de Revistas Científicas - FM/MCP
Artigos e Materiais de Revistas Científicas - HC/InCor
Artigos e Materiais de Revistas Científicas - ODS/03