Please use this identifier to cite or link to this item: https://observatorio.fm.usp.br/handle/OPI/35738
Title: Changes in cartilage, synovial cells and synovial fluid after malleolar fractures: What its importance for post-traumatic ankle osteoarthitis?
Authors: GODOY-SANTOS, A.L.LOPES, D.GIAROLA, I.CESAR NETTO, C. deRAMMELT, S.
Citation: FUSS UND SPRUNGGELENK, v.17, n.2, p.68-74, 2019
Abstract: Background: Despite advances in malleolar fractures treatment, the overall risk to develop posttraumatic ankle osteoarthritis after 20 years is almost 40%, especially bimalleolar Weber type B and C fractures and fractures involving the posterior tibial rim. Methods: We performed a systematic literature review of clinical studies targeting the changes in cartilage, synovial cells and synovial fluid after malleolar fractures. Results: The acute ankle injury initiates a sequence of biological events potentially leading to progressive articular surface damage resulting from inflammatory changes in cartilage, synovial tissue and synovial fluid. Conclusion: A better understanding of the molecular and histological changes induced by acute trauma may potentially lead to novel, targeted treatment of malleolar fractures besides anatomical reduction and adequate stabilization. © 2019
Appears in Collections:

Artigos e Materiais de Revistas Científicas - FM/MFT
Departamento de Fisioterapia, Fonoaudiologia e Terapia Ocupacional - FM/MFT

Artigos e Materiais de Revistas Científicas - HC/IOT
Instituto de Ortopedia e Traumatologia - HC/IOT

Artigos e Materiais de Revistas Científicas - LIM/34
LIM/34 - Laboratório de Ciências da Reabilitação

Artigos e Materiais de Revistas Científicas - LIM/41
LIM/41 - Laboratório de Investigação Médica do Sistema Músculoesquelético


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