Next-generation sequencing of circulating tumor DNA for metastatic non-small cell lung cancer: a discussion on its implementation in the Brazilian clinical practice

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Citações na Scopus
2
Tipo de produção
article
Data de publicação
2020
Título da Revista
ISSN da Revista
Título do Volume
Editora
FUTURE MEDICINE LTD
Autores
ARAUJO, Luiz H
FERREIRA, Carlos Gil
BALDOTTO, Clarissa S.
MATHIAS, Clarissa
COUDRY, Renata
Citação
FUTURE ONCOLOGY, v.17, n.2, p.205-214, 2020
Projetos de Pesquisa
Unidades Organizacionais
Fascículo
Resumo
The objective of this review is to address the barriers limiting access to next-generation sequencing (NGS) of circulating tumor DNA (ctDNA) for metastatic nonsquamous non-small cell lung cancer in Brazil and to propose its implementation in practice. A selected panel of lung cancer experts was provided with relevant prompts to address at a conference; a paper was then compiled on the topic. The authors propose specific and realistic recommendations for implementing access to ctDNA NGS. Further, the authors address all barriers and impediments mentioned within this review. There is a great need to increase ctDNA NGS for cancer care in Brazil. Adapting the current cancer testing framework is essential to expanding the use of this tool.
Palavras-chave
Brazil, circulating tumor DNA, metastatic, next-generation sequencing, NGS, non-small cell lung cancer, NSCLC
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