Biomarkers of human papillomavirus (HPV)-driven head and neck cancer in Latin America and Europe study: Study design and HPV DNA/p16(INK4a) status

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art_SICHERO_Biomarkers_of_human_papillomavirus_HPVdriven_head_and_neck_2022.PDF (1022.77 KB)
Citações na Scopus
3
Tipo de produção
article
Data de publicação
2022
DOI
Scopus
Web of Science
PubMed
Título da Revista
ISSN da Revista
Título do Volume
Editora
WILEY
Autores
TAGLIABUE, Marta
CASTANEDA, Carlos Arturo
CASTILLO, Miluska
CORREA, Rita Mariel
PERDOMO, Sandra
RODRIGUEZ-URREGO, Paula A.
Citação
HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK, v.44, n.1, p.122-133, 2022
Projetos de Pesquisa
Unidades Organizacionais
Fascículo
Resumo
Background Human papillomavirus (HPV)-driven head/neck squamous cell carcinomas (HNSCC) prevalence varies globally. We evaluated HPV DNA and p16(INK4a) in formalin fixed paraffin embedded (FFPE) HNSCC from Argentina, Brazil, Colombia, and Peru. Methods HPV was genotyped by PCR-hybridization. All HPV DNA positive and some HPV DNA negative cases underwent p16(INK4a) immunohistochemistry. Results HPV DNA was detected in 32.8%, 11.1%, and 17.8% of oropharyngeal (OPC), oral cavity (OCC) and laryngeal (LC) cancers, respectively. OPC HPV prevalence was higher in Colombia (94.7%), and Argentina (42.6%) compared to Brazil (10.6%) and Peru (0.0%). HPV-16 was the most detected. Other HPVs were found in LC. Higher rates of p16(INK4a) positivity were observed among HPV positive OPC/OCC cases compared to LC cases. Conclusions Our results support a role for HPV-16 in a subset of HNSCC, corroborate the heterogeneity observed in samples from different countries, and contribute additional etiological and biomarkers information in tumors of significant impact worldwide.
Palavras-chave
head and neck cancer, human papillomavirus, multinational study, prevalence, risk factors
URI
https://observatorio.fm.usp.br/handle/OPI/44419
Referências
  1. Abrahao R, 2020, JCO GLOB ONCOL, V6, P486, DOI 10.1200/GO.20.00014
  2. Anantharaman D, 2013, JNCI-J NATL CANCER I, V105, P536, DOI 10.1093/jnci/djt053
  3. Ang KK, 2010, NEW ENGL J MED, V363, P24, DOI 10.1056/NEJMoa0912217
  4. Betiol JC, 2016, INFECT AGENTS CANCER, V11, DOI 10.1186/s13027-016-0067-8
  5. Blas MM, 2015, PLOS ONE, V10, DOI 10.1371/journal.pone.0139524
  6. Boscolo-Rizzo P, 2018, PLOS ONE, V13, DOI 10.1371/journal.pone.0192621
  7. Boscolo-Rizzo P, 2016, CANCER TREAT REV, V42, P24, DOI 10.1016/j.ctrv.2015.10.009
  8. Castellsague X, 2016, JNCI-J NATL CANCER I, V108, DOI 10.1093/jnci/djv403
  9. Castillo A, 2011, WORLD J GASTROENTERO, V17, P5295, DOI 10.3748/wjg.v17.i48.5295
  10. Chaturvedi AK, 2013, J CLIN ONCOL, V31, P4550, DOI 10.1200/JCO.2013.50.3870
  11. D'Souza G, 2016, ORAL ONCOL, V62, P20, DOI 10.1016/j.oraloncology.2016.09.005
  12. de Matos LL, 2015, BRAZ J OTORHINOLAR, V81, P554, DOI 10.1016/j.bjorl.2015.04.001
  13. de Sanjose S, 2018, JNCI CANCER SPECT, V2, DOI 10.1093/jncics/pky045
  14. Fakhry C, 2018, J CLIN ONCOL, V36, P3152, DOI 10.1200/JCO.18.00684
  15. Ferlay J, 2010, INT J CANCER, V127, P2893, DOI 10.1002/ijc.25516
  16. Gheit T, 2017, INT J CANCER, V141, P143, DOI 10.1002/ijc.30712
  17. Gillison ML, 2019, GENOME RES, V29, P1, DOI 10.1101/gr.241141.118
  18. Gillison ML, 2014, INT J CANCER, V134, P497, DOI 10.1002/ijc.28201
  19. Gonzalez JV, 2007, MEDICINA-BUENOS AIRE, V67, P363
  20. Hauck F, 2015, VIRCHOWS ARCH, V466, P685, DOI 10.1007/s00428-015-1761-4
  21. Criscuolo MI, 2020, MED ORAL PATOL ORAL, V25, pE425, DOI 10.4317/medoral.23462
  22. Isayeva T, 2012, HEAD NECK PATHOL, V6, pS104, DOI 10.1007/s12105-012-0368-1
  23. Kaminagakura E, 2012, INT J CANCER, V130, P1726, DOI 10.1002/ijc.26185
  24. Lawrence MS, 2015, NATURE, V517, P576, DOI 10.1038/nature14129
  25. Li H, 2018, JAMA OTOLARYNGOL, V144, P519, DOI 10.1001/jamaoto.2018.0395
  26. Marur S, 2010, LANCET ONCOL, V11, P781, DOI 10.1016/S1470-2045(10)70017-6
  27. Mattoscio D, 2017, PLOS PATHOG, V13, DOI 10.1371/journal.ppat.1006262
  28. Mattoscio D, 2015, FUTURE ONCOL, V11, P1599, DOI 10.2217/fon.15.41
  29. Mena M, 2017, PLOS ONE, V12, DOI 10.1371/journal.pone.0184520
  30. Lopez RVM, 2014, CANCER CAUSE CONTROL, V25, P461, DOI 10.1007/s10552-014-0348-8
  31. Nasman A, 2009, INT J CANCER, V125, P362, DOI 10.1002/ijc.24339
  32. Nygard M, 2012, EUR J CANCER, V48, P1341, DOI 10.1016/j.ejca.2012.03.014
  33. Quintero K, 2013, BRAZ J OTORHINOLAR, V79, P375, DOI 10.5935/1808-8694.20130065
  34. Ribeiro KB, 2011, INT J EPIDEMIOL, V40, P489, DOI 10.1093/ije/dyq249
  35. Rosen BJ, 2016, SEX TRANSM INFECT, V92, P149, DOI 10.1136/sextrans-2014-051942
  36. Sung H, 2021, CA-CANCER J CLIN, V71, P209, DOI 10.3322/caac.21660
  37. SYRJANEN K, 1983, INT J GYNECOL OBSTET, V21, P261, DOI 10.1016/0020-7292(83)90015-2
  38. Syrjanen S, 2011, ORAL DIS, V17, P58, DOI 10.1111/j.1601-0825.2011.01792.x
  39. Tagliabue M, 2020, CANCERS, V12, DOI 10.3390/cancers12123567
  40. Walter L, 2014, HEAD NECK-J SCI SPEC, V36, P729, DOI 10.1002/hed.23369
  41. Winn DM, 2015, ORAL DIS, V21, P685, DOI 10.1111/odi.12342

Coleções
Artigos e Materiais de Revistas Científicas - FM/MDR
Artigos e Materiais de Revistas Científicas - HC/ICESP
Artigos e Materiais de Revistas Científicas - LIM/08
Artigos e Materiais de Revistas Científicas - LIM/24
Artigos e Materiais de Revistas Científicas - ODS/03