Clinically significant changes in health-related quality of life in head and neck cancer patients following intensive nutritional care during radiotherapy

Imagem de Miniatura
Arquivos
art_FARIA_Clinically_significant_changes_in_healthrelated_quality_of_life_2022.PDF (1.66 MB)
Citações na Scopus
6
Tipo de produção
article
Data de publicação
2022
DOI
Scopus
Web of Science
PubMed
Título da Revista
ISSN da Revista
Título do Volume
Editora
ELSEVIER SCI LTD
Autores
CARVALHO, Andre Lopes
MARTA, Gustavo Nader
HOWELL, Doris
Citação
EUROPEAN JOURNAL OF ONCOLOGY NURSING, v.56, article ID 102065, 6p, 2022
Projetos de Pesquisa
Unidades Organizacionais
Fascículo
Resumo
Purpose: This study aimed to explore whether adherence to intensive nutritional care during radiotherapy would avoid a meaningful worsening in quality of life in head and neck cancer patients; and whether adherence was associated with better nutritional outcomes. Methods: Observational prospective study that assessed head and neck cancer patients treated with radiotherapy at a large oncology hospital, between August 2018 and April 2019. The main outcome was minimal clinically important difference in quality of life, assessed with EORTC QLQ-C30 and EORTC QLQ H&N35, between baseline and 12 weeks. To illustrate clinically significant changes in quality of life over timeby adherence, a heat map analysis was performed. We also evaluated nutritional outcomes. Results: Eighty patients were included, half of them (53.8%) were considered adherent. There were no significant difference in quality of life between groups at baseline, with the exception of swallowing (p = 0.029) and coughing (p < 0.01). After treatment, the heat map demonstrated that adherent patients had nonsignificant clinical change in function scales, while non-adherent patients had a clinically significant worsening in physical, cognitive and social function. The prevalence of malnutrition increased significantly only in non-adherent patients (p < 0.01). Conclusion: Adherence to intensive nutritional care may be able to avoid a meaningful worsening in quality of life and result in better nutritional outcomes in head and neck cancer patients. Our results may help to increase the awareness of the assessment of adherence and minimal clinically important difference in quality of life for research purposes and clinical practice.
Palavras-chave
Adherence, Head neck cancer, Health related quality of life, Nutrition support, Quality of life, Treatment
URI
https://observatorio.fm.usp.br/handle/OPI/48524
Referências
  1. Amin MB, 2017, CA-CANCER J CLIN, V67, P93, DOI 10.3322/caac.21388
  2. Arends J, 2017, CLIN NUTR, V36, P11, DOI 10.1016/j.clnu.2016.07.015
  3. Arribas L, 2017, ORAL ONCOL, V71, P67, DOI 10.1016/j.oraloncology.2017.06.003
  4. Axelsson L, 2017, HEAD NECK-J SCI SPEC, V39, P908, DOI 10.1002/hed.24707
  5. Bicakli DH, 2017, J NUTR METAB, V2017, DOI 10.1155/2017/8631945
  6. Binenbaum Y, 2014, ANN SURG ONCOL, V21, P2773, DOI 10.1245/s10434-014-3656-z
  7. Bjordal K, 1999, J CLIN ONCOL, V17, P1008, DOI 10.1200/JCO.1999.17.3.1008
  8. BJORDAL K, 1994, ACTA ONCOL, V33, P879, DOI 10.3109/02841869409098450
  9. Cereda E, 2018, RADIOTHER ONCOL, V126, P81, DOI 10.1016/j.radonc.2017.10.015
  10. Crosby RD, 2003, J CLIN EPIDEMIOL, V56, P395, DOI 10.1016/S0895-4356(03)00044-1
  11. Faria SD, 2021, EUR ARCH OTO-RHINO-L, V278, P3507, DOI 10.1007/s00405-020-06550-2
  12. de van der Schueren MAE, 2018, ANN ONCOL, V29, P1141, DOI 10.1093/annonc/mdy114
  13. Faria SD, 2021, J HUM NUTR DIET, V34, P562, DOI 10.1111/jhn.12848
  14. Fearon K, 2011, LANCET ONCOL, V12, P489, DOI 10.1016/S1470-2045(10)70218-7
  15. Findlay M, 2013, ASIA-PAC J CLIN ONCO, V9, P70
  16. Funk GF, 2004, ARCH OTOLARYNGOL, V130, P825, DOI 10.1001/archotol.130.7.825
  17. Hofto Sophie, 2018, Cancers Head Neck, V3, P6, DOI 10.1186/s41199-018-0033-9
  18. Hong FX, 2013, BMC CANCER, V13, DOI 10.1186/1471-2407-13-165
  19. JAESCHKE R, 1989, CONTROL CLIN TRIALS, V10, P407, DOI 10.1016/0197-2456(89)90005-6
  20. Jeffery E, 2018, ASIA PAC J CLIN NUTR, V27, P955, DOI 10.6133/apjcn.122017.05
  21. Kimura H, 2020, INT J CLIN ONCOL, V25, P258, DOI 10.1007/s10147-019-01560-5
  22. Kristensen MB, 2020, NUTRITION, V69, DOI 10.1016/j.nut.2019.06.028
  23. KUYKEN W, 1995, SOC SCI MED, V41, P1403, DOI 10.1016/0277-9536(95)00112-k
  24. Langius JAE, 2013, CLIN NUTR, V32, P671, DOI 10.1016/j.clnu.2013.06.012
  25. Maringwa JT, 2011, SUPPORT CARE CANCER, V19, P1753, DOI 10.1007/s00520-010-1016-5
  26. Marta GN, 2017, ANN PALLIAT MED, V6, P73, DOI 10.21037/apm.2016.11.09
  27. Mulasi U, 2020, NUTR CLIN PRACT, V35, P1129, DOI 10.1002/ncp.10476
  28. Musoro JZ, 2020, HEAD NECK-J SCI SPEC, V42, P3141, DOI 10.1002/hed.26363
  29. Network N.C.C, 2020, NCCN GUID HEAD NECK
  30. Orell H, 2019, FRONT NUTR, V6, DOI 10.3389/fnut.2019.00022
  31. Osoba D, 1998, J CLIN ONCOL, V16, P139, DOI 10.1200/JCO.1998.16.1.139
  32. Ottery FD, 1996, NUTRITION, V12, pS15, DOI 10.1016/0899-9007(95)00067-4
  33. Pandit P, 2020, NUTR CLIN PRACT, V35, P1047, DOI 10.1002/ncp.10488
  34. Pezdirec M, 2019, RADIOL ONCOL, V53, P225, DOI 10.2478/raon-2019-0028
  35. Ravasco P, 2019, J CLIN MED, V8, DOI 10.3390/jcm8081211
  36. Ringash J, 2007, CANCER-AM CANCER SOC, V110, P196, DOI 10.1002/cncr.22799
  37. Roussel LM, 2017, EUR ARCH OTO-RHINO-L, V274, P977, DOI 10.1007/s00405-016-4278-9
  38. Sandmael JA, 2019, EUR J CANCER CARE, V28, DOI 10.1111/ecc.13168
  39. Silander E, 2012, HEAD NECK-J SCI SPEC, V34, P1, DOI 10.1002/hed.21700
  40. Sung H, 2021, CA-CANCER J CLIN, V71, P209
  41. Talwar B, 2016, J LARYNGOL OTOL, V130, pS32, DOI 10.1017/S0022215116000402
  42. Vahdat S, 2014, IRAN RED CRESCENT ME, V16, DOI 10.5812/ircmj.12454
  43. van den Berg MGA, 2006, CLIN NUTR, V25, P765, DOI 10.1016/j.clnu.2005.12.007
  44. Vartanian J.G., 2007, REV BRAS CIR CABECA, V36, P108
  45. Vartanian JG, 2017, CURR OPIN ONCOL, V29, P159, DOI 10.1097/CCO.0000000000000369
  46. White JV, 2012, JPEN-PARENTER ENTER, V36, P275, DOI 10.1177/0148607112440285
  47. WHO Consultation, 2000, WHO TECH REP SER, V894, P1
  48. Yost KJ, 2005, EVAL HEALTH PROF, V28, P172, DOI 10.1177/0163278705275340

Coleções
Artigos e Materiais de Revistas Científicas - FM/MPR
Artigos e Materiais de Revistas Científicas - LIM/38
Artigos e Materiais de Revistas Científicas - ODS/02
Artigos e Materiais de Revistas Científicas - ODS/03