aPDT for oral decontamination of hospitalized patients with COVID 19
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Citações na Scopus
6
Tipo de produção
article
Data de publicação
2022
Título da Revista
ISSN da Revista
Título do Volume
Editora
ELSEVIER
Autores
MORIMOTO, Susana
ROSIN, Joao Luiz Azevedo
SCHROTER, Gabriella
RODRIGUES, Maria Fernanda Setubal Destro
RAMALHO, Karen M.
RAGGIO, Daniela Procida
MOREIRA, Maria Stella
Citação
PHOTODIAGNOSIS AND PHOTODYNAMIC THERAPY, v.38, article ID 102762, 3p, 2022
Resumo
Emerging variants of severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2) may have an impact on the virus's transmissibility and pathogenicity and an increased risk of reinfection. Antimicrobial photodynamic therapy (aPDT) is a promising technique to decontaminate the oral cavity to minimize and inactivate micro -organisms' load. This article reports through a case series, a proposal for efficient oral decontamination for hospitalized patients with COVID 19 using aPDT. Samples of oral tissues were obtained after aPDT and analyzed using two methods of RT-qPCR to elucidate qualitative and quantitative viral profiles of SARS-CoV-2 RNA in the oral cavity. There was a reduction of viral load in the oral cavity immediately or one hour after the use of aPDT. This method could be a good option to decontaminate the oral cavity to minimize and inactivate microorganism load.
Palavras-chave
COVID-19, SARS-CoV-2, Photodynamic therapies, Oral decontamination
Referências
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