Long-term effects of COVID-19 in diabetic and non-diabetic patients

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Citações na Scopus
4
Tipo de produção
article
Data de publicação
2022
Título da Revista
ISSN da Revista
Título do Volume
Editora
FRONTIERS MEDIA SA
Citação
FRONTIERS IN PUBLIC HEALTH, v.10, article ID 963834, 5p, 2022
Projetos de Pesquisa
Unidades Organizacionais
Fascículo
Resumo
The literature presents several reports of the impact of glycemic control and diabetes in the inflammatory and coagulatory response during coronavirus disease 2019 (COVID-19). Nevertheless, the long-term impact of the COVID-19 in diabetic patients is still to be explored. Therefore, we recruited 128 patients and performed a longitudinal analysis on COVID-19-associated biomarkers of patients with COVID-19, tree and 6 months after COVID-19 recovery and put into perspective the possible long-term complication generated after COVID-19. In our investigation, we failed to verify any long-term modification on inflammatory biomarkers, but detected an increase in the glycemia and glycated hemoglobin in patients without any pre-existing history or diagnosis of diabetes (non-diabetic patients). Although diabetic and non-diabetic patients presented elevated levels of glycated hemoglobin, the c-peptide test indicated a normal beta cell function in all patients.
Palavras-chave
SARS-CoV-2, COVID-19, complications, glycemic control, infection
Referências
  1. Akter F, 2020, DIABETES METAB SYND, V14, P2031, DOI 10.1016/j.dsx.2020.10.016
  2. Alberca RW, 2021, FRONT PHYSIOL, V11, DOI 10.3389/fphys.2020.637627
  3. Alberca RW, 2020, FRONT MED-LAUSANNE, V7, DOI 10.3389/fmed.2020.580677
  4. Alberca RW., 2021, TRANSPLANTOLOGY, V2, P296, DOI [10.3390/transplantology2030030, DOI 10.3390/TRANSPLANTOLOGY2030030]
  5. Berbudi A, 2020, CURR DIABETES REV, V16, P442, DOI 10.2174/1573399815666191024085838
  6. de Leon AC, 2015, DIABETES VASC DIS RE, V12, P199, DOI 10.1177/1479164114564900
  7. Dan JM, 2021, SCIENCE, V371, P587, DOI 10.1126/science.abf4063
  8. Gangadharan C, 2021, WORLD J DIABETES, V12, P1550, DOI 10.4239/wjd.v12.i9.1550
  9. Kamal M, 2021, INT J CLIN PRACT, V75, DOI 10.1111/ijcp.13746
  10. Khunti K, 2021, DIABETES CARE, V44, P2645, DOI 10.2337/dc21-1318
  11. Lee DH, 2003, DIABETOLOGIA, V46, P359, DOI 10.1007/s00125-003-1036-5
  12. Lopez-Leon S, 2021, SCI REP-UK, V11, DOI [10.1038/s41598-021-95565-8, 10.1101/2021.01.27.21250617]
  13. Lumlertgul N, 2021, ANN INTENSIVE CARE, V11, DOI 10.1186/s13613-021-00914-5
  14. Mustafa AK, 2021, J CURR MED RES PRACT, V6, P134, DOI [10.4103/JCMRP.JCMRP_111_18, DOI 10.4103/JCMRP.JCMRP_111_18]
  15. Phetsouphanh C, 2021, MEDRXIV, DOI [10.1101/2021.06.01.21257759, DOI 10.1101/2021.06.01.21257759]
  16. Sachdeva Sonali, 2020, SN Compr Clin Med, V2, P2161, DOI 10.1007/s42399-020-00575-8
  17. Sousa BLA, 2020, CLINICS, V75, DOI 10.6061/clinics/2020/e2273
  18. Temgoua Mazou Ngou, 2020, SN Compr Clin Med, V2, P1377, DOI 10.1007/s42399-020-00417-7
  19. Wang AH, 2020, DIABETES RES CLIN PR, V162, DOI 10.1016/j.diabres.2020.108118
  20. Wu CT, 2021, CELL METAB, V33, P1565, DOI 10.1016/j.cmet.2021.05.013
  21. Yanez ND, 2020, BMC PUBLIC HEALTH, V20, DOI 10.1186/s12889-020-09826-8