Heat exposure and hospitalisation for epileptic seizures: A nationwide case-crossover study in Brazil

Imagem de Miniatura
Arquivos
art_ZHANG_Heat_exposure_and_hospitalisation_for_epileptic_seizures_A_2023.PDF (1.48 MB)
Citações na Scopus
1
Tipo de produção
article
Data de publicação
2023
DOI
Scopus
Web of Science
Título da Revista
ISSN da Revista
Título do Volume
Editora
ELSEVIER
Autores
ZHANG, Yiwen
XU, Rongbin
YE, Tingting
YU, Wenhua
YU, Pei
CHEN, Zhuying
MAHENDRAN, Rahini
GUO, Yuming
Citação
URBAN CLIMATE, v.49, article ID 101497, 11p, 2023
Projetos de Pesquisa
Unidades Organizacionais
Fascículo
Resumo
Climate change is increasing human exposure to heat, especially in tropical regions such as Brazil where temperature reaches up to 40 degrees C in summer. However, the association between heat exposure and epileptic seizures has not been well demonstrated in Brazil, where lifetime preva-lence of epilepsy can range from 11.9/1000 to 21/1000. We collected a total of 225,699 hospi-talisation records for epileptic seizures of 1816 municipalities in Brazil, during the hot season from 2000 to 2015, covering nearly 79% of the national population. We implemented a time -stratified case-crossover design combined with distributed lag model with further stratified in-vestigations regarding sex, age, socioeconomic status and region. We found temperature impact threshold was 26 degrees C in Brazil nationally. Every 1 degrees C increase from the threshold was associated with an overall 4.3% increased risk of hospitalisation for epileptic seizures on the current day of hospital admission and up to seven days before, which was most pronounced on the second-day exposure to heat. Females, individuals aged 20-30 and persons living in high-income or Southeast regions were more vulnerable. Our results highlight the enhanced risk of heat exposure for epi-lepsy patients and could contribute to epilepsy management, such as forecasting epileptic sei-zures. Multi-dimensional adaptive strategies were proposed, covering individual protection, occupational health surveillance, and urban planning management, aiming to reduce heat -induced hospitalisations for epilepsy, and be generalizable to other heat-related diseases.
Palavras-chave
Heatwave, Epilepsy, epileptic seizures, Climate change, Neurological disease, Case -crossover study
URI
https://observatorio.fm.usp.br/handle/OPI/54049
Referências
  1. Altimiras-Roset J, 2014, REV NEUROLOGIA, V59, P345, DOI 10.33588/rn.5908.2014115
  2. Beghi E, 2019, LANCET NEUROL, V18, P357, DOI 10.1016/S1474-4422(18)30454-X
  3. Berg AT, 2012, NEUROLOGY, V78, P444, DOI 10.1212/WNL.0b013e318246d70b
  4. Bras PC, 2018, EPILEPSY BEHAV, V86, P25, DOI 10.1016/j.yebeh.2018.07.010
  5. Burkart K, 2011, ENVIRON POLLUT, V159, P2035, DOI 10.1016/j.envpol.2011.02.005
  6. Chang KC, 2019, EPILEPSY BEHAV, V100, DOI 10.1016/j.yebeh.2019.04.036
  7. Chien LC, 2016, SCI TOTAL ENVIRON, V562, P845, DOI 10.1016/j.scitotenv.2016.04.042
  8. de Albuquerque MV, 2017, CIENC SAUDE COLETIVA, V22, P1055, DOI 10.1590/1413-81232017224.26862016
  9. Fisher RS, 2005, EPILEPSIA, V46, P470, DOI 10.1111/j.0013-9580.2005.66104.x
  10. Gaitatzis A, 2004, BRAIN, V127, P2427, DOI 10.1093/brain/awh267
  11. Gasparrini A, 2010, STAT MED, V29, P2224, DOI 10.1002/sim.3940
  12. Gulcebi MI, 2021, EPILEPSY BEHAV, V116, DOI 10.1016/j.yebeh.2021.107791
  13. Guo Y., 2023, HEAT EXPOSURE HUMAN, P293
  14. Hansen A, 2008, ENVIRON HEALTH PERSP, V116, P1369, DOI 10.1289/ehp.11339
  15. He BJ, 2022, BUILD ENVIRON, V208, DOI 10.1016/j.buildenv.2021.108587
  16. Heaviside Clare, 2017, Curr Environ Health Rep, V4, P296, DOI 10.1007/s40572-017-0150-3
  17. Li LM, 2007, ARQ NEURO-PSIQUIAT, V65, P5, DOI 10.1590/S0004-282X2007001000002
  18. Li XJ, 2008, SEIZURE-EUR J EPILEP, V17, P254, DOI 10.1016/j.seizure.2007.07.011
  19. Lin JN, 2018, COMPUT ELECTR ENG, V68, P437, DOI 10.1016/j.compeleceng.2018.04.020
  20. Malta DC, 2016, INT J EQUITY HEALTH, V15, DOI 10.1186/s12939-016-0427-4
  21. McHugh JC, 2008, INT REV NEUROBIOL, V83, P11, DOI 10.1016/S0074-7742(08)00002-0
  22. Mewasingh LD, 2020, DEV MED CHILD NEUROL, V62, P1245, DOI 10.1111/dmcn.14642
  23. Moshe SL, 2015, LANCET, V385, P884, DOI 10.1016/S0140-6736(14)60456-6
  24. Noelke C, 2016, ENVIRON RES, V151, P124, DOI 10.1016/j.envres.2016.06.045
  25. Obradovich N, 2017, SCI ADV, V3, DOI 10.1126/sciadv.1601555
  26. Rakers F, 2017, EPILEPSIA, V58, P1287, DOI 10.1111/epi.13776
  27. Reis J, 2021, J Neurol Sci, V421, P117287, DOI 10.1016/j.jns.2020.117287
  28. Ruegg S, 2008, EPILEPSY BEHAV, V12, P66, DOI 10.1016/j.yebeh.2007.08.020
  29. Salvati KA, 2019, BRAIN RES, V1703, P41, DOI 10.1016/j.brainres.2017.12.037
  30. Savic I, 2014, NEUROBIOL DIS, V70, P69, DOI 10.1016/j.nbd.2014.05.028
  31. Shibasaki K, 2020, LAB INVEST, V100, P274, DOI 10.1038/s41374-019-0335-5
  32. Tomasovic S, 2022, BMC NEUROL, V22, DOI 10.1186/s12883-021-02535-8
  33. WHO, 2019, ICD 10 VERS 2019
  34. Xavier AC, 2016, INT J CLIMATOL, V36, P2644, DOI 10.1002/joc.4518
  35. Xiong J, 2015, PHYSIOL BEHAV, V151, P426, DOI 10.1016/j.physbeh.2015.07.037
  36. Xu RB, 2020, LANCET PLANET HEALTH, V4, pE566, DOI 10.1016/S2542-5196(20)30251-5
  37. Xu RB, 2019, ENVIRON HEALTH PERSP, V127, DOI 10.1289/EHP5688
  38. Xu RB, 2019, PLOS MED, V16, DOI 10.1371/journal.pmed.1002950
  39. Zammit C, 2021, EARLY HUM DEV, V155, DOI 10.1016/j.earlhumdev.2020.105217
  40. Zhao Q, 2022, SCI TOTAL ENVIRON, V849, DOI 10.1016/j.scitotenv.2022.157836
  41. Zhao Q, 2021, LANCET PLANET HEALTH, V5, pE415, DOI 10.1016/S2542-5196(21)00081-4
  42. Zhao Q, 2019, THORAX, V74, P1031, DOI 10.1136/thoraxjnl-2019-213486
  43. Zhao Q, 2019, PLOS MED, V16, DOI 10.1371/journal.pmed.1002753
  44. Zhao Q, 2018, ENVIRON INT, V120, P345, DOI 10.1016/j.envint.2018.08.021

Coleções
Artigos e Materiais de Revistas Científicas - FM/MPT
Artigos e Materiais de Revistas Científicas - HC/InCor
Artigos e Materiais de Revistas Científicas - LIM/05
Artigos e Materiais de Revistas Científicas - ODS/11
Artigos e Materiais de Revistas Científicas - ODS/13