Clinical Aspects and Etiologic Investigation of Pediatric Patients With Acute Liver Failure
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article
Data de publicação
2023
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Editora
ELSEVIER SCIENCE INC
Citação
TRANSPLANTATION PROCEEDINGS, v.55, n.9, 2023
Resumo
A new outbreak of hepatitis of unknown origin raised awareness in the international community. A few reports have attempted to associate new cases with adenovirus infection and the immunologic effects of previous SARS-CoV-2 infections through a superantigen mechanism. Moreover, according to a case series, viral isolates were identified in 7 of 10 cases of pediatric patients with hepatitis of unknown origin and acute liver failure. Adenovirus was detected by respiratory secretion polymerase chain reaction in 2 patients, with neither presenting with SARS-CoV-2 acute infection. Clinical and laboratory descriptions and cross-referencing epidemiologic and pathophysiological data can help identify possible disease etiologies.
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Referências
- Alberto LD, 2015, Rev Med Minas Gerais, V25, pS44
- Tannuri ACA, 2016, LIVER TRANSPLANT, V22, P1006, DOI 10.1002/lt.24435
- Bernal W, 2013, NEW ENGL J MED, V369, P2525, DOI 10.1056/NEJMra1208937
- Brodin P, 2022, LANCET GASTROENTEROL, V7, P594, DOI 10.1016/S2468-1253(22)00166-2
- Castaldo Eric T, 2006, HPB (Oxford), V8, P29, DOI 10.1080/13651820500465741
- CDC Health Alert Network, Recommendations for adenovirus testing and reporting of children with acute hepatitis of unknown etiology
- Colleti J, 2019, REV ASSOC MED BRAS, V65, P914, DOI 10.1590/1806-9282.65.6.914
- Czaja AJ, 2016, GUT LIVER, V10, P177, DOI 10.5009/gnl15352
- Deep A, 2022, INTENS CARE MED, V48, P958, DOI 10.1007/s00134-022-06765-3
- Sanchez LHG, 2022, NEW ENGL J MED, V387, P620, DOI 10.1056/NEJMoa2206294
- Narkewicz MR, 2009, J PEDIATR-US, V155, P801, DOI 10.1016/j.jpeds.2009.06.005
- United Kingdom Health Security Agency (UKHSA), 2022, Increase in acute hepatitis cases of unknown aetiology in children
- World Health Organization (WHO), 2022, Disease Outbreak news
- acute hepatitis of unknown aetiology in children-multi-country