• Myokines in treatment-na & iuml;ve patients with cancer-associated cachexia 

  CASTRO, Gabriela S. de; CORREIA-LIMA, Joanna; SIMOES, Estefania; ORSSO, Camila E.; XIAO, Jingjie; GAMA, Leonardo R.; GOMES, Silvio P.; GONCALVES, Daniela Caetano; COSTA, Raquel G. F.; RADLOFF, Katrin; LENZ, Ulrike; TARANKO, Anna E.; BIN, Fang Chia; FORMIGA, Fernanda B.; GODOY, Louisie G. L. de; SOUZA, Rafael P. de; NUCCI, Luis H. A.; FEITOZA, Mario; CASTRO, Claudio C. de; TOKESHI, Flavio; ALCANTARA, Paulo S. M.; OTOCH, Jose P.; RAMOS, Alexandre F.; LAVIANO, Alessandro; COLETTI, Dario; MAZURAK, Vera C.; PRADO, Carla M.; SEELAENDER, Marilia (CHURCHILL LIVINGSTONE, EDINBURGH, SCOTLAND, 2021)

  Cancer-associated cachexia is a complex metabolic syndrome characterized by weight loss and systemic inflammation. Muscle loss and fatty infiltration into muscle are associated with poor prognosis in cancer patients. ...
• Exercise Training Preserves Myocardial Strain and Improves Exercise Tolerance in Doxorubicin-Induced Cardiotoxicity 

  GOMES-SANTOS, Igor L.; JORDAO, Camila P.; PASSOS, Clevia S.; BRUM, Patricia C.; OLIVEIRA, Edilamar M.; CHAMMAS, Roger; CAMARGO, Anamaria A.; NEGRAO, Carlos E. (FRONTIERS MEDIA SA, LAUSANNE, SWITZERLAND, 2021)

  Doxorubicin causes cardiotoxicity and exercise intolerance. Pre-conditioning exercise training seems to prevent doxorubicin-induced cardiac damage. However, the effectiveness of the cardioprotective effects of exercise ...
• Global incidence trends in head and neck cancer for HPV-related and -unrelated subsites: A systematic review of population-based studies 

  MENEZES, Fabricio dos Santos; FERNANDES, Gisele Aparecida; ANTUNES, Jose Leopoldo Ferreira; VILLA, Luisa Lina; TOPORCOV, Tatiana Natasha (ELSEVIER, AMSTERDAM, NETHERLANDS, 2021)

  In head and neck cancer (HNC), some subsites are associated with human papillomavirus (HPV) infection, whereas others are unrelated. Although studies have demonstrated the heterogeneity of HPV prevalence worldwide, its ...
• Serum Creatinine as a Potential Biomarker of Skeletal Muscle Atrophy in Non-small Cell Lung Cancer Patients 

  NEVES, Willian das; ALVES, Christiano R. R.; BORGES, Ana Paula de Souza; JR, Gilberto de Castro (FRONTIERS MEDIA SA, LAUSANNE, SWITZERLAND, 2021)

  Objectives: Identifying simple biomarkers to determine muscle atrophy in non-small-cell lung cancer (NSCLC) patients remains a critical research gap. Since creatinine is mainly a product from intramuscular creatine metabolism, ...
• Revealing the BRD4-NOTCH3 fusion: A novel hill in the cancer landscape 

  COSTA, Fabiano de Almeida; AMANO, Mariane Tami; ASPRINO, Paula Fontes; PAVLICK, Dean C.; MASOTTI, Cibele; TESTAGROSSA, Leonardo; JR, Gilberto de Castro (ELSEVIER IRELAND LTD, CLARE, IRELAND, 2021)

  Objectives: Gene fusions are becoming more evident in cancer scenario for either being the driver alterations, or for the great therapeutic target potential in many cases. Our aim was to characterize the BRD4-NOTCH3 fusion ...
• Metformin impairs cisplatin resistance effects in A549 lung cancer cells through mTOR signaling and other metabolic pathways 

  MORELLI, Ana Paula; TORTELLI, Tharcisio Citrangulo Jr Jr; PAVAN, Isadora Carolina Betim; SILVA, Fernando Riback; GRANATO, Daniela Campos; PERUCA, Guilherme Francisco; PAULETTI, Bianca Alves; DOMINGUES, Romenia Ramos; BEZERRA, Rosangela Maria Neves; MOURA, Leandro Pereira De; LEME, Adriana Franco Paes; CHAMMAS, Roger; SIMABUCO, Fernando Moreira (SPANDIDOS PUBL LTD, ATHENS, GREECE, 2021)

  Lung cancer is the leading cause of cancer-associated death worldwide and exhibits intrinsic and acquired therapeutic resistance to cisplatin (CIS). The present study investigated the role of mTOR signaling and other ...
• Low RECK Expression Is Part of the Cervical Carcinogenesis Mechanisms 

  HERBSTER, Suellen; TROMBETTA-LIMA, Marina; SOUZA-SANTOS, Paulo Thiago de; PALADINO, Andressa; SILVEIRA, Caio Raony Farina; SOGAYAR, Mari Cleide; VILLA, Luisa Lina; LEPIQUE, Ana Paula; BOCCARDO, Enrique (MDPI, BASEL, SWITZERLAND, 2021)

  Simple Summary Cervical cancer is one of the most lethal types of cancer in women from developing countries. These tumors are caused by long term infection with some human papillomavirus (HPV) types. Commonly, cervical ...
• Susceptibility loci for pancreatic cancer in the Brazilian population 

  AOKI, Mateus Nobrega; STEIN, Angelika; OLIVEIRA, Jaqueline Carvalho de; CHAMMAS, Roger; UNO, Miyuki; MUNHOZ, Francielle Bocon de Araujo; MARIN, Anelis Maria; CANZIAN, Federico (BMC, LONDON, ENGLAND, 2021)

  BackgroundPancreatic adenocarcinoma (PA) is a very aggressive cancer and has one of the poorest prognoses. Usually, the diagnosis is late and resistant to conventional treatment. Environmental and genetic factors contribute ...
• Exercise prescription for symptoms and quality of life improvements in lung cancer patients: a systematic review 

  CODIMA, Alberto; SILVA, Willian das Neves; BORGES, Ana Paula de Souza; JR, Gilberto de Castro (SPRINGER, NEW YORK, UNITED STATES, 2021)

  Purpose The purpose of this study was to conduct a systematic review to assess the effect of exercise on symptoms and quality of life in lung cancer patients. Methods We conducted a systematic review using the Preferred ...
• The hidden curve behind COVID-19 outbreak: the impact of delay in treatment initiation in cancer patients and how to mitigate the additional risk of dying-the head and neck cancer model 

  MATOS, Leandro L.; FORSTER, Carlos Henrique Q.; MARTA, Gustavo N.; CASTRO JUNIOR, Gilberto; RIDGE, John A.; HIRATA, Daisy; MIRANDA-FILHO, Adalberto; HOSNY, Ali; SANABRIA, Alvaro; GREGOIRE, Vincent; PATEL, Snehal G.; FAGAN, Johannes J.; D'CRUZ, Anil K.; LICITRA, Lisa; MEHANNA, Hisham; HAO, Sheng-Po; PSYRRI, Amanda; PORCEDDU, Sandro; GALLOWAY, Thomas J.; GOLUSINSKI, Wojciech; LEE, Nancy Y.; SHIGUEMORI, Elcio H.; MATIELI, Jose Elias; SHIGUEMORI, Ana Paula A. C.; DIAMANTINO, Leticia R.; SCHIAVETO, Luiz Felipe; LEAO, Lysia; CASTRO, Ana F.; CARVALHO, Andre Lopes; KOWALSKI, Luiz Paulo (SPRINGER, DORDRECHT, NETHERLANDS, 2021)

  Purpose The rapid spread of the SARS-CoV-2 pandemic around the world caused most healthcare services to turn substantial attention to treatment of these patients and also to alter the structure of healthcare systems to ...
• The impact of socioeconomic status on HPV infection among young Brazilians in a nationwide multicenter study 

  KOPS, Natalia L.; HORVATH, Jaqueline D. C.; BESSEL, Marina; SOUZA, Flavia M. A.; BENZAKEN, Adele S.; PEREIRA, Gerson F. M.; VILLA, Luisa L.; WENDLAND, Eliana M. (ELSEVIER, AMSTERDAM, NETHERLANDS, 2021)

  The aim of this study is to evaluate genital human papillomavirus (HPV) infection according to socioeconomic categories in Brazil. This cross-sectional, nationwide study included 7,694 sexually active women and men aged ...
• Effectiveness of a universal vaccination program with an HPV quadrivalent vaccine in young Brazilian women 

  WENDLAND, Eliana M.; KOPS, Natalia Luiza; BESSEL, Marina; COMERLATO, Juliana; MARANHAO, Ana Goretti Kalume; SOUZA, Flavia Moreno Alves; VILLA, Luisa Lina; PEREIRA, Gerson Fernando Mendes (ELSEVIER SCI LTD, OXFORD, ENGLAND, 2021)

  We examined human papillomavirus (HPV) vaccine effectiveness in a nationwide sample of women aged 16 to 25 years who utilized the public health system in Brazil. This was a cross-sectional, multicentric survey conducted ...
• Dynamic changes in white matter following traumatic brain injury and how diffuse axonal injury relates to cognitive domain 

  GRASSI, Daphine Centola; ZANINOTTO, Ana Luiza; FELTRIN, Fabricio Stewan; MACRUZ, Fabiola Bezerra Carvalho; OTADUY, Maria Concepcion Garcia; LEITE, Claudia Costa; GUIRADO, Vinicius Monteiro Paula; PAIVA, Wellingson Silva; ANDRADE, Celi Santos (TAYLOR & FRANCIS LTD, ABINGDON, ENGLAND, 2021)

  Objective: The goal is to evaluate longitudinally with diffusion tensor imaging (DTI) the integrity of cerebral white matter in patients with moderate and severe DAI and to correlate the DTI findings with cognitive deficits. ...
• Prevalence of human papillomavirus 6 and 11 variants in recurrent respiratory papillomatosis 

  SICHERO, Laura; FERREIRA, Silvaneide; LOPEZ, Rossana V. M.; MELLO, Barbara P.; COSTA, Victor; EL-ACHKAR, Vivian N. R.; CARLOS, Roman; RIBEIRO-SILVA, Alfredo; PIGNATARI, Shirley; KAMINAGAKURA, Estela; VILLA, Luisa L. (WILEY, HOBOKEN, USA, 2021)

  Human papillomavirus (HPV) types 6 and 11 are the etiological agents of recurrent respiratory papillomatosis (RRP). We examined the prevalence and distribution of HPVs 6 and 11 genetic variants in juvenile onset (JORRP) ...
• Feasibility of SBRT for hepatocellular carcinoma in Brazil - a prospective pilot study 

  CHEN, Andre Tsin Chih; PAYAO, Fabio; CHAGAS, Aline Lopes; ALENCAR, Regiane Saraiva De Souza Melo; TANI, Claudia Megumi; VASCONCELOS, Karina Gondim Moutinho da Conceicao; ROCHA, Manoel De Souza; CARVALHO, Heloisa De Andrade; HOFF, Paulo Marcelo Gehm; CARRILHO, Flair Jose (VIA MEDICA, GDANSK, POLAND, 2021)

  Background: The aim of the study was to evaluate the feasibility and safety of stereotactic body radiotherapy (SBRT) for the treatment of hepatocellular carcinoma in Brazil. SBRT is an evolving treatment in HCC patients ...
• PET/MRI Characterization of Mucinous Versus Nonmucinous Components of Rectal Adenocarcinoma: A Comparison of Tumor Metabolism and Cellularity 

  QUEIROZ, Marcelo A.; NAVES, Anarosa; DREYER, Priscilla R.; CERRI, Giovanni G.; BUCHPIGUEL, Carlos A. (AMER ROENTGEN RAY SOC, LEESBURG, USA, 2021)

  OBJECTIVE. The purpose of this study was to evaluate whether FDG PET/MRI can be used to differentiate the mucinous from the nonmucinous components of primary rectal tumors and to compare the glycolytic metabolism on PET ...
• Is it Safe to Perform Elective Colorectal Surgical Procedures during the COVID-19 Pandemic? A Single Institution Experience with 103 Patients 

  SOBRADO, Lucas Faraco; NAHAS, Caio Sergio Rizkallah; MARQUES, Carlos Frederico Sparapan; COTTI, Guilherme Cutait de Castro; IMPERIALE, Antonio Rocco; AVERBACH, Pedro; MEIRA JR., Jose Donizeti de; HORVAT, Natally; RIBEIRO JR., Ulysses; CECCONELLO, Ivan; NAHAS, Sergio Carlos (HOSPITAL CLINICAS, UNIV SAO PAULO, SAO PAULO, BRAZIL, 2021)

  OBJECTIVES: Since the outbreak of the novel coronavirus disease 2019 (COVID-19), all health services worldwide underwent profound changes, leading to the suspension of many elective surgeries. This study aimed to evaluate ...
• 11C-PK11195 plasma metabolization has the same rate in multiple sclerosis patients and healthy controls: a cross-sectional study 

  SOUZA, Aline Morais de; PITOMBEIRA, Milena Sales; SOUZA, Larissa Estessi de; MARQUES, Fabio Luiz Navarro; BUCHPIGUEL, Carlos Alberto; REAL, Caroline Cristiano; FARIA, Daniele de Paula (WOLTERS KLUWER MEDKNOW PUBLICATIONS, MUMBAI, INDIA, 2021)

  11C-PK11195 is a positron emitter tracer used for Positron Emission Tomography (PET) imaging of innate immune cell activation in studies of neuroinflammatory diseases. For the image quantitative analysis, it is necessary ...
• PHLDA3 (pleckstrin homology-like domain, family A, member 3) 

  FERREIRA, M.P.; NAGAI, M.A. (ATLAS OF GENETICS AND CYTOGENETICS IN ONCOLOGY AND HAEMATOLOGY, 2020)

  Review on PHLDA3, with data on DNA, on the protein encoded, and where the gene is implicated. © 2020 Atlas of Genetics and Cytogenetics in Oncology and Haematology.
• ACC Glu/GABA ratio is decreased in euthymic bipolar disorder I patients: possible in vivo neurometabolite explanation for mood stabilization 

  SCOTTI-MUZZI, Estevao; CHILE, Thais; MORENO, Ricardo; PASTORELLO, Bruno Fraccini; LEITE, Claudia da Costa; HENNING, Anke; OTADUY, Maria Concepcion Garcia; VALLADA, Homero; SOEIRO-DE-SOUZA, Marcio Gerhardt (SPRINGER HEIDELBERG, HEIDELBERG, GERMANY, 2021)

  Bipolar disorder (BD) is characterized by unstable mood states ranging from mania to depression. Although there is some evidence that mood instability may result from an imbalance between excitatory glutamatergic and ...

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