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1. Epidemiology of Abdominal Aortic Aneurysm Repair in Brazil from 2008 to 2019 and Comprehensive Review of Nationwide Statistics Across the World

   WORLD JOURNAL OF SURGERY, v.46, n.6, p.1485-1492, 2022

   Introduction Studying epidemiology of abdominal aortic aneurysms repairs is essential to prevent related deaths. Although outcomes are influenced by socioeconomic factors, there are no nationwide studies on these statistics in low-and-middle income countries. Therefore, we designed this study to ...

2. Segmental cardiac strain assessment by two-dimensional speckle-tracking echocardiography in surviving MIS-c patients: Correlations with myocardial flow reserve (MFR) by 13 N-ammonia PET-CT

   MICROCIRCULATION, v.29, n.3, article ID e12750, 11p, 2022

   Background Multisystem inflammatory syndrome in children (MIS-c) is associated with severe cardiovascular impairment and eventually death. Pathophysiological mechanisms involved in myocardial injury were scarcely investigated, and cardiovascular outcomes are uncertain. Autopsy studies suggested t...

3. <p>Pembrolizumab alone or with chemotherapy for recurrent or metastatic head and neck squamous cell carcinoma: Health-related quality-of-life results from KEYNOTE-048</p>

   ORAL ONCOLOGY, v.128, article ID 105815, 12p, 2022

   Objectives: To assess health-related quality of life (HRQoL) with first-line pembrolizumab, pembrolizumabchemotherapy, or cetuximab-chemotherapy in recurrent or metastatic head and neck squamous cell carcinoma (R/M HNSCC) in the phase 3 KEYNOTE-048 trial (NCT02358031).& nbsp;Materials and Methods...

4. METNET: a phase II trial of metformin in patients with well-differentiated neuroendocrine tumours

   ECANCERMEDICALSCIENCE, v.16, article ID 1369, 14p, 2022

   Background: Preclinical studies have suggested that metformin has anti-tumour effects, likely due to blockage of mammalian target of rapamycin pathway through adenosine monophosphate-activated protein kinase and decreased insulin levels. A retrospective study showed that metformin added to everol...

5. Longitudinal whole-brain analysis of multi-subject diffusion data in diffuse axonal injury

   ARQUIVOS DE NEURO-PSIQUIATRIA, v.80, n.3, p.280-288, 2022

   Background: Diffuse axonal injury occurs with high acceleration and deceleration forces in traumatic brain injury (TBI). This lesion leads to disarrangement of the neuronal network, which can result in some degree of deficiency. The Extended Glasgow Outcome Scale (GOS-E) is the primary outcome in...

6. Disruption of miRNA-mRNA Networks Defines Novel Molecular Signatures for Penile Carcinogenesis

   CANCERS, v.13, n.19, article ID 4745, 19p, 2021

   Simple Summary: As there are still no biomarkers reported in clinical practice in penile cancer (PeC), we aimed to investigate and validate molecular signatures based on miRNA and mRNA profiles to identify molecular drivers and pathways involved in PeC tumorigenesis. We found eight DEmiRs and 37 ...

7. TLR4 and SARM1 modulate survival and chemoresistance in an HPV-positive cervical cancer cell line

   SCIENTIFIC REPORTS, v.12, n.1, article ID 6714, 12p, 2022

   Human Papillomavirus is responsible for a wide range of mucosal lesions and tumors. The immune system participate in tumorigenesis in different ways. For example, signaling pathways triggered by Toll-like receptors (TLR) play a role in chemotherapy resistance in several tumor types and are candid...

8. A Diagnostic Algorithm for Posterior Fossa Tumors in Children: A Validation Study

   AMERICAN JOURNAL OF NEURORADIOLOGY, v.42, n.5, p.961-968, 2021

   BACKGROUND AND PURPOSE: Primary posterior fossa tumors comprise a large group of neoplasias with variable aggressiveness and short and long-term outcomes. This study aimed to validate the clinical usefulness of a radiologic decision flow chart based on previously published neuroradiologic knowled...

9. <p>Prevalence and persistence of HPV-16 molecular variants in the anal canal of men: The HIM study</p>

   JOURNAL OF CLINICAL VIROLOGY, v.149, article ID 105128, 7p, 2022

   Background: HPV-16 causes approximately 90% of anal canal (AC) cancers worldwide. This study aimed to evaluate the prevalence and persistence of HPV-16 genetic variants in the AC of men from three different countries (Brazil, Mexico and United States) and to further identify sociodemographic and ...

10. Non-Small-Cell Lung Cancer With CNS Metastasis: Disparities From a Real-World Analysis (GBOT-LACOG 0417)

    JCO GLOBAL ONCOLOGY, v.8, article ID e2100333, 11p, 2022

    PURPOSE Despite the advances in the approach to non-small-cell lung cancer (NSCLC) with CNS metastasis, access to timely diagnosis and treatment may not be optimal in many instances. Our main objective was to describe a cohort of patients with NSCLC with brain metastases from public and private c...