Effect of adding clonidine to lidocaine on ocular hemodynamics during sub-Tenon’s anesthesia: randomized double-blind study

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art_CABRAL_Effect_of_adding_clonidine_to_lidocaine_on_ocular_2021_eng.PDF (772.98 KB)
Citações na Scopus
3
Tipo de produção
article
Data de publicação
2021
DOI
SciELO
Scopus
Web of Science
Título da Revista
ISSN da Revista
Título do Volume
Editora
Sociedade Brasileira de Anestesiologia (SBA)
Autores
CABRAL, Sigmar Aurea
CARRARETTO, Antonio Roberto
GOMEZ, Renato Santiago
Citação
BRAZILIAN JOURNAL OF ANESTHESIOLOGY, v.71, n.6, p.628-634, 2021
Projetos de Pesquisa
Unidades Organizacionais
Fascículo
Resumo
Abstract Introduction and objectives Different regional anesthesia techniques for ophthalmology can have hemodynamic effects on the eye. We assessed the effects of adding clonidine to lidocaine on Intraocular Pressure (IOP), Ocular Pulse Amplitude (OPA), and Ocular Perfusion Pressure (OPP) after the sub-Tenon’s technique for cataract surgery. Methods The study included 40 patients randomly allocated into two groups: sub-Tenon’s blockade with Lidocaine plus Saline Solution (LS) or Lidocaine plus Clonidine (LC). IOP, OPA and OPP were measured before anesthesia, and 1, 5 and 10 minutes after the injection of anesthetic solution. Results There was no difference between the groups in IOP, OPA, and OPP baseline values. After the injection of the anesthetic solution, the IOP increased in both groups at minute one, with a mean difference of +4.67 mmHg (p= 0.001) and +2.15 mmHg (p= 0.013) at 5 minutes. The increase was lower in the LC group when compared to LS (p= 0.027). OPA decreased in both groups, with a baseline difference, after 1 minute, of -0.85 mmHg (p = -0.85 mmHg (p= 0.001), and at 5 and 10 minutes with differences of -1.17 (p= 0.001) and -0.89 mmHg (p= 0.001), respectively. The highest decrease was observed in group LC in relation to group LS (p= 0.03). There was no difference in OPP in relation to baseline measurements. Conclusions Adding clonidine to lidocaine for sub-Tenon’s anesthesia reduced IOP and OPA without significant changes in OPP.
Palavras-chave
Sub-Tenon’s anesthesia, Clonidine, Intraocular pressure, Ocular pulse amplitude, Ocular perfusion pressure, Cataract surgery
URI
https://observatorio.fm.usp.br/handle/OPI/44864
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Coleções
Artigos e Materiais de Revistas Científicas - HC/ICESP
Artigos e Materiais de Revistas Científicas - HC/ICHC
Artigos e Materiais de Revistas Científicas - LIM/08