A comparison of the cardiopulmonary effects of pressure controlled ventilation and volume controlled ventilation in healthy anesthetized dogs
Carregando...
Citações na Scopus
17
Tipo de produção
article
Data de publicação
2016
Título da Revista
ISSN da Revista
Título do Volume
Editora
WILEY-BLACKWELL
Autores
LOPES, Thomas F. T.
Citação
JOURNAL OF VETERINARY EMERGENCY AND CRITICAL CARE, v.26, n.4, p.524-530, 2016
Resumo
Objective - To compare the effects of pressure controlled ventilation (PCV) with volume-controlled ventilation (VCV) on lung compliance, gas exchange, and hemodynamics in isoflurane-anesthetized dogs. Design - Prospective randomized study. Setting - Veterinary teaching hospital. Animals - Forty client-owned bitches undergoing elective ovariohysterectomy. Interventions - Dogs were randomly assigned to be ventilated with 100% oxygen using PCV (n = 20) or VCV (n = 20). The respiratory rate was 20/min and positive end-expiratory pressure (PEEP) was 5 cm H2O, with a tidal volume of 10 mL/kg. Cardiac output (CO) was measured using thermodilution. Cardiopulmonary and blood gas data were obtained during spontaneous ventilation and after 30 (T30) and 60 minutes (T60) of controlled ventilation. Measurements and Main Results - In dogs ventilated with PCV, at T30 and T60, PIP was lower (11.4 +/- 1.9 and 11.1 +/- 1.5 cm H2O, respectively) and static compliance (C-ST) was higher (51 +/- 7 and 56 +/- 6 mL/cm H2O, respectively) than in VCV group (PIP of 14.3 +/- 1.3 and 15.5 +/- 1.4 cm H2O; C-ST of 34 +/- 8 and 33 +/- 9 mL/cm H2O, P < 0.0001). Compared with spontaneous ventilation, both groups had decreased alveolar-arterial oxygen difference at T30 and T60 (PCV: 128 +/- 32 mm Hg vs 108 +/- 20 and 104 +/- 16 mm Hg, respectively; VCV: 131 +/- 38 mm Hg vs 109 +/- 19 and 107 +/- 14 mm Hg, respectively; P < 0.01), while CO was maintained at all time points. Conclusions - Compared to spontaneous ventilation, both ventilatory modes effectively improved gas exchange without hemodynamic impairment. PCV resulted in higher lung C-ST and lower PIP compared to VCV.
Palavras-chave
canine, mechanical ventilation, pulmonary function, respiratory mechanics
Referências
- ABRAHAM E, 1990, CHEST, V98, P1445, DOI 10.1378/chest.98.6.1445
- ALSAADY N, 1985, INTENS CARE MED, V11, P68
- Campbell Robert S, 2002, Respir Care, V47, P416
- Canfran S, 2012, VET J, V194, P89, DOI 10.1016/j.tvjl.2012.02.021
- Corona TM, 2011, J VET EMERG CRIT CAR, V21, P496, DOI 10.1111/j.1476-4431.2011.00673.x
- Drummheller OJ, 2012, FDN RESP CARE, P116
- HOLT JP, 1968, AM J PHYSIOL, V215, P704
- Hopper K, 2007, JAVMA-J AM VET MED A, V230, P64, DOI 10.2460/javma.230.1.64
- Lim SC, 2004, CRIT CARE MED, V32, P2378, DOI 10.1097/01.CCM.0000147444.58070.72
- Lucangelo Umberto, 2005, Respir Care, V50, P55
- Marini JJ, 1994, PRINCIPLES PRACTICE, P305
- McMillan MW, 2009, J VET EMERG CRIT CAR, V19, P564, DOI 10.1111/j.1476-4431.2009.00480.x
- Oura T, 2012, J VET EMERG CRIT CAR, V22, P368, DOI 10.1111/j.1476-4431.2012.00749.x
- Pinheiro BV, 2002, J PNEUMOL, V28, P5
- Prella M, 2002, CHEST, V122, P1382, DOI 10.1378/chest.122.4.1382
- Putensen C, 2002, ANESTHESIOLOGY, V97, P652, DOI 10.1097/00000542-200209000-00020
- Riquelme M, 2005, AM J VET RES, V66, P978, DOI 10.2460/ajvr.2005.66.978
- Staffieri F, 2010, VET RES COMMUN, V34, pS131, DOI 10.1007/s11259-010-9405-2
- Staffieri F, 2010, AM J VET RES, V71, P867, DOI 10.2460/ajvr.71.8.867
- Tusman Gerardo, 2010, Best Pract Res Clin Anaesthesiol, V24, P183